Neurological Associate Pain Management Center

Vero Beach, Florida

Venipuncture CRPS II

We would like to hear from any CRPS/RSD patient who developed their CRPS/RSD from a "Venipuncture Injury" (needle injury, e.g., blood test, I.V. infiltration). Venipuncture CRPS II is one of the most severe and painful forms of CRPS/RSD that a patient can develop.

Doctors Hooshmand, Hashmi and Eric M. Phillips have co-authored the following article: Venipuncture Complex Regional Pain Syndrome Type II which was published in the American Journal of Pain Management in October 2001. This article is a case study of 22 Venipuncture CRPS II patients.

If you have questions regarding Venipuncture CRPS II, please feel free to contact me at:  When, you e-mail me, please put Venipuncture CRPS II in the subject line.

Below is an abstract from the article Venipuncture Complex Regional Pain Syndrome Type II.

Please click on the link below to view the full text of this article in PDF-format.

Venipuncture CRPS-II Article


Case Report


Hooshang Hooshmand, M.D., Masood Hashmi, M.D. and Eric M. Phillips


Abstract - Venipuncture Complex Regional Pain Syndrome Type II (VP CRPS II) is a rare and unpredictable complication of venipuncture. It is the prototype of a minor injury leading to a severe form of CRPS. It should not be mistaken for benign forms of hematoma or phlebitis without CRPS. There is no definite causal relation to the type of needle used, nor to number of attempts at I.V. insertion. It is usually a rare happenstance complication of the needle accidentally injuring the microscopic microvascular c-thermoreceptor sensory nerves. Lack of experience and severity of the trauma are not proven risk factors. There is no known preventive measure. Accidental infiltration of chemical irritants can instigate the VP CRPS- unless the injection is discontinued immediately. Early diagnosis, and proper treatment provide significant pain relief. 

Descriptors: Causalgia, CRPS I and II, Neuroinflammation, Spread of CRPS, Sympathectomy, Venipuncture.

Hooshmand H, Hashmi M, and Phillips E.M. Venipuncture Complex Regional Pain Syndrome Type II. AJPM 2001; 11: 112-124.

Received: 1-30-01 Accepted:5-23-01